12.06.2023 • NewsArtificial IntelligenceMicroscopy

AI-based workflow for confocal microscopy automates the detection of rare events

Leica Microsystems, an expert in microscopy and scientific instrumentation, has launched an autonomous microscopy package.

Autonomous Microscopy powered by Aivia enables scientists to discover more by extracting the most relevant data from their experiments. It follows what the user has defined as the objects of interest that will trigger the rare event scan. Users are able to discover more by automatically detecting up to 90 % of rare events during an experiment. By focusing on the data that matter during the acquisition process itself, time to result can be reduced by up to 70 %. The Aivia-powered workflow reduces time spent at the microscope by up to 75 %, leading to increased productivity to do more.

The detection and analysis of rare events in biological samples is relevant in...
The detection and analysis of rare events in biological samples is relevant in research fields like cancer and Alzheimer’s disease. The image shows a mitosis detected with Autonomous Microscopy powered by Aivia. (Source: Leica)

The rare event detection workflow is based on the interaction of two components available on a Stellaris confocal system. Often, overview scans of the biological sample are analyzed. If the Aivia AI-based image analysis software detects indications of a rare event, the positions are sent back to the controlling software of Stellaris which is called Navigator Expert. The positions of the identified events are automatically scanned at high resolution and in three dimensions based on the user's defined settings.

With Autonomous Microscopy powered by Aivia, operator interaction is limited to the initial setup. Objects are detected  faster and accurately. The same settings can be applied for other experiments to ensure consistency. Because only objects of interest are identified and captured, data acquisition and final analysis time is reduced. This exclusivity also means an extreme saving of storage space.

Company

Leica Microsystems GmbH

Ernst-Leitz-Str. 17-37
35578 Wetzlar
Germany

Company contact







Digital Events

Digital Event Calendar 2025
live or on demand

Digital Event Calendar 2025

By participating in our free digital events, you can stay up to date in your field of expertise.

Award

AutomationsBest Award

AutomationsBest Award

The AutomationsBest Award is now entering its 3rd round. The award will be presented at SPS - Smart Production Solutions on 25 November 2025

most read

Photo
26.06.2025 • News

Optical knots made of laser beams

Interference patterns between overlapping laser beams could transmit encoded information over thousands of feet through chaotic environments.